CBX3 Antibody HRP conjugated

Volume : 50 µg
Clone Number :
Aliases : CBX 3 antibody; CBX3 antibody; CBX3_HUMAN antibody; Chromobox homolog 3 (HP1 gamma homolog; Drosophila) antibody; Chromobox homolog 3 antibody; Chromobox protein homolog 3 antibody; GAMMA antibody; HECH antibody; Heterochromatin like protein 1 antibody; Heterochromatin protein 1 homolog gamma antibody; Heterochromatin protein HP1 gamma antibody; HP1 gamma antibody; HP1 gamma homolog antibody; HP1Hs gamma antibody; Modifier 2 protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q13185
Immunogen : Recombinant Human Chromobox protein homolog 3 protein (10-122AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at \'Lys-9\', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane thro µgh its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore thro µgh interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state thro µgh H3 \'Lys-9\' trimethylation, mediates the recruitment of the methyltransferases SUV39H1 and/or SUV39H2 by the PER complex to the E-box elements of the circadian target genes such as PER2 itself or PER1.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CBX3
Research Areas : Epigenetics and Nuclear Signaling