AURKAIP1 Antibody

Volume : 50 µL
Clone Number :
Aliases : 28S ribosomal protein S38 antibody; AIP antibody; AKIP_HUMAN antibody; AURKA interacting protein antibody; AURKA-interacting protein antibody; AURKAIP 1 antibody; Aurkaip1 antibody; Aurora A kinase interacting protein antibody; Aurora kinase A interacting protein 1 antibody; Aurora kinase A-interacting protein antibody; FLJ20608 antibody; mitochondrial antibody; MRP-S38 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NWT8
Immunogen : Fusion protein of Human AURKAIP1
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA, WB; ELISA : 1 : 2000-1 : 5000, WB : 1 : 500-1 : 2000
Background : AKIP (AURKA-interacting protein), also known as AURKAIP1 (aurora kinase A interacting protein 1) or AIP, is a 199 amino acid protein that localizes to the nucleus and is ubiquitously expressed, with highest levels present in testis, heart and skeletal muscle. Interacting specifically with ARK-1 (aurora kinase 1), AKIP functions to induce the proteasomal-dependent degradation of ARK-1 thereby acting as a negative reg µLator of ARK-1 activity. AKIP is encoded by a gene which maps to human chromosome 1 which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and m µLtiple myeloma.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen affinity purification
Conj µgate : Non-conj µgated
Buffer : -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AURKAIP1
Research Areas : Cancer;Cell biology