MRP-14(MRP14/840) , 0.2mg / mL

Recognizes a protein of14 kDa , identified as MRP-14 (also known as Calgranulin B or S100AA9). It comprises 60% of the cytoplasmic protein fraction of circulating polymorphonuclear granulocytes and is also found in monocytes , macrophages and ileal tissue eosinophils. Peripheral blood monocytes carry the antigen extra- and intracellularly , neutrophils only intracellularly. It is a potent chemotactic factor for neutrophils. Plasma concentrations are elevated in diseases associated with increased neutrophil activity , like inflammatory bowel disease. Granulocytes terminate their existence after transmigration through the intestinal wall. Therefore , it is also detectable in feces. Elevated levels have been observed in body fluids such as plasma , saliva , gingival crevicular fluid , stools , and synovial fluid during infection and inflammatory conditions. This MAb reacts with neutrophils , monocytes , and macrophages , and has been shown as an important marker for identifying macrophages in tissue sections.This antibody is available purified with BSA/azide at 200 ug/ mL , or BSA/azide-free at 1 mg / mL.