MHC I(246-B8E7) , 0.2mg / mL

Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A , B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes , thymocytes , granulocytes , and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation , inhibition of NK cell cytotoxicity , tumor surveillance , and tissue allotransplantation.Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.