BRAP Monoclonal Antibody
Volume : 100 µL
Clone Number :
Aliases : 3010002G07Rik; BRAP2; BRCA1 associated protein; EC 6.3.2.; Galectin 2 binding protein; IMP; Impedes mitogenic signal propagation; Renal carcinoma antigen NY REN 63; RING finger protein 52; RNF52; zgc : 92894.
Product Type : Monoclonal Antibody
Immunogen Species : Human
UniProt ID : Q7Z569
Immunogen : Purified recombinant human BRAP protein fragments expressed in E.coli.
Raised in : Mouse
Species Reactivity : Human
Tested Applications : ELISA,WB;Recommended dilution : WB : 1 : 500-1 : 5000
Background : Negatively reg µLates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination res µLting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in reg µLating nuclear transport.
Clonality : Monoclonal
Isotype : IgG1
Purification Method : Affinity purified
Conj µgate : Non-conj µgated
Buffer : Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BRAP
Research Areas : Epigenetics and Nuclear Signaling;Signal transduction