DEAF1 Antibody HRP conjugated

Volume : 50 µg
Clone Number :
Aliases : Deaf1 antibody; DEAF1 transcription factor antibody; DEAF1_HUMAN antibody; Deformed epidermal autoreg µLatory factor 1 homolog antibody; Nuclear DEA1 related transcriptional reg µLator antibody; Nuclear DEAF-1-related transcriptional reg µLator antibody; NUDR antibody; SPN antibody; Suppressin antibody; Zinc finger MYND domain containing protein 5 antibody; Zinc finger MYND domain-containing protein 5 antibody; ZMYND5 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O75398
Immunogen : Recombinant Human Deformed epidermal autoreg µLatory factor 1 homolog protein (73-200AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Transcription factor that binds to sequence with m µLtiple copies of 5\'-TTC[CG]G-3\' present in its own promoter and that of the HNRPA2B1 gene. Down-reg µLates transcription of these genes. Binds to the retinoic acid response element (RARE) 5\'-AGGGTTCACCGAAAGTTCA-3\'. Activates the proenkephalin gene independently of promoter binding, probably thro µgh protein-protein interaction. When secreted, behaves as an inhibitor of cell proliferation, by arresting cells in the G0 or G1 phase. Required for neural tube closure and skeletal patterning. Reg µLates epithelial cell proliferation and side-branching in the mammary gland. Controls the expression of peripheral tissue antigens in pancreatic lymph nodes. Isoform 1 displays greater transcriptional activity than isoform 4. Isoform 4 may inhibit transcriptional activity of isoform 1 by interacting with isoform 1 and retaining it in the cytoplasm. Transcriptional activator of EIF4G3.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DEAF1
Research Areas : Epigenetics and Nuclear Signaling; Cell biology