DNAJB6 Antibody FITC conjugated

Volume : 50 µg
Clone Number :
Aliases : DJ4 antibody; DnaJ antibody; DnaJ (Hsp40) homolog subfamily B member 6 antibody; DNAJ B6 antibody; DnaJ homolog subfamily B member 6 antibody; DnaJ like 2 protein antibody; DNAJB6 antibody; DNJB6_HUMAN antibody; Heat shock protein J2 antibody; HHDJ1 antibody; HSJ-2 antibody; HSJ2 antibody; LGMD1E antibody; MRJ antibody; MSJ-1 antibody; MSJ1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O75190
Immunogen : Recombinant Human DnaJ homolog subfamily B member 6 protein (208-326AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molec µLar chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins. Isoform B but not isoform A inhibits huntingtin aggregation. Has a stim µLatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Also reduces cell µLar toxicity and caspase-3 activity.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNAJB6
Research Areas : Neuroscience; Signal transduction