DKK1 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : Dickkopf 1 antibody; Dickkopf 1 homolog antibody; Dickkopf 1 like antibody; Dickkopf homolog 1 antibody; Dickkopf like protein 1 antibody; Dickkopf related protein 1 antibody; Dickkopf WNT signaling pathway inhibitor 1 antibody; Dickkopf-1 antibody; Dickkopf-related protein 1 antibody; DKK 1 antibody; Dkk-1 antibody; Dkk1 antibody; DKK1_HUMAN antibody; hDkk 1 antibody; hDkk-1 antibody; SK antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O94907
Immunogen : Recombinant Human Dickkopf-related protein 1 protein (33-266AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt reg µLated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the ad µLt, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DKK1
Research Areas : Cardiovasc µLar; Developmental biology; Immunology; Stem cells