DIS3L2 Antibody HRP conjugated

Volume : 50 µg
Clone Number :
Aliases : DI3L2_HUMAN antibody; DIS3 L2 antibody; DIS3 mitotic control homolog (S. cerevisiae) like 2 antibody; DIS3 mitotic control homolog like 2 antibody; DIS3-like exonuclease 2 antibody; Dis3l2 antibody; FLJ36974 antibody; MGC42174 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8IYB7
Immunogen : Recombinant Human DIS3-like exonuclease 2 protein (201-400AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : 3\'-5\'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3\' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3\'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mitosis, and negatively reg µLates cell proliferation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DIS3L2
Research Areas : Cell biology