DOCK3 Antibody HRP conjugated

Volume : 50 µg
Clone Number :
Aliases : DOCK3 antibody; KIAA0299 antibody; MOCADedicator of cytokinesis protein 3 antibody; Modifier of cell adhesion antibody; Presenilin-binding protein antibody; PBP antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8IZD9
Immunogen : Recombinant Human Dedicator of cytokinesis protein 3 protein (1630-1934AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Potential guanine nucleotide exchange factor (GEF). GEF proteins activate some small GTPases by exchanging bound GDP for free GTP. Its interaction with presenilin proteins as well as its ability to stim µLate Tau/MAPT phosphorylation s µggest that it may be involved in Alzheimer disease. Ectopic expression in nerve cells decreases the secretion of beta-amyloid APBA1 protein and lowers the rate of cell-substratum adhesion, s µggesting that it may affect the function of some small GTPase involved in the reg µLation of actin cytoskeleton or cell adhesion receptors (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DOCK3
Research Areas : Neuroscience; Stem cells