Cobra venom factor Antibody

Volume : 50 µg
Clone Number :
Aliases : antibody; Cobra venom factor antibody; CVF antibody; CVFk antibody; Complement C3 homolog) [Cleaved into : Cobra venom factor alpha chain; Cobra venom factor gamma chain; Cobra venom factor beta chain] antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Naja kaouthia
UniProt ID : Q91132
Immunogen : Recombinant Naja kaouthia Cobra venom factor protein (733-984AA)
Raised in : Rabbit
Species Reactivity : Naja kaouthia
Tested Applications : ELISA, WB; Recommended dilution : WB : 1 : 500-1 : 5000
Background : Complement-activating protein in cobra venom. It is a structural and functional analog of complement component C3b, the activated form of C3. It binds factor B (CFB), which is subsequently cleaved by factor D (CFD) to form the bimolec µLar complex CVF/Bb. CVF/Bb is a C3/C5 convertase that cleaves both complement components C3 and C5. Structurally, it resembles the C3b degradation product C3c, which is not able to form a C3/C5 convertase. Unlike C3b/Bb, CVF/Bb is a stable complex and completely resistant to the actions of complement reg µLatory factors H (CFH) and I (CFI). Therefore, CVF continuously activates complement res µLting in the depletion of complement activity.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Non-conj µgated
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names :
Research Areas : Others