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IGKV1 5 antibody

https://www.hugenavigator.net/web/image/product.template/91720/image_1920?unique=cd1bae2

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : V segment of the variable domain of immunoglob µLins light chain that participates to the antigen recognition. Immunoglob µLins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglob µLins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglob µLins-secreting plasma cells. Secreted immunoglob µLins mediate the effector phase of humoral immunity, which res µLts in the elimination of bound antigens(PubMed : 20176268, PubMed : 22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglob µLin has two antigen binding sites with remarkable affinity for a partic µLar antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a partic µLar antigen(PubMed : 20176268, PubMed : 17576170).
Immunogen : immunoglob µLin kappa variable 1-5
Aliases :
Observed MW :
Uniprot ID : P01602
Reactivity : Human, Mouse
Application : ELISA, WB
Recommended dilution : WB : 1 : 500-1 : 2000
Gene ID :
Research Area : Immunology

331,65 € 331.65 EUR 331,65 €

331,65 €

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Expédition : 2-3 jours ouvrables